PATHOLOGY 7310

Week 1

Serogroup Conversion of Vibrio cholerae in Aquatic Reservoirs

RpoS Controls the Vibrio cholerae Mucosal Escape Response

Chitin Induces Natural Competence in Vibrio cholerae

Week 2

Lentiviral Vpr usurps Cul4–DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle

Manipulation of the Ubiquitin/Proteasome System by Viruses - Planelles Lecture

Week 3

The inflammation-associated Salmonella SopA is a HECT-like E3 ubiquitin ligase

Salmonella enterica Serovar Typhimurium Exploits Inflammation to Compete with the Intestinal Microbiota

Differential activation and function of Rho GTPases during Salmonella–host cell interactions

Week 4

Staphylococcus aureus

Poring over pores: α-hemolysin and Panton-Valentine leukocidin in Staphylococcus aureus pneumonia

Is Panton-Valentine Leukocidin the Major Virulence Determinant in Community-Associated Methicillin-Resistant Staphylococcus aureus Disease?

Vaccine protection against Staphylococcus aureus pneumonia

Staphylococcus aureus Panton-Valentine Leukocidin Causes Necrotizing Pneumonia

Identification of novel cytolytic peptides as key virulence determinants for community-associated MRSA

Week 5

Pathogens vs. Innate Immunity

Mannose-binding lectin enhances Toll-like receptors 2 and 6 signaling from the phagosome

Induction of APOBEC3G Ubiquitination and Degradation by an HIV-1 Vif-Cul5-SCF Complex

An Endogenous Inhibitor of Human Immunodeficiency Virus in Human Lymphocytes Is Overcome by the Viral Vif Protein

Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein

Week 6

Borrelia burgdorferi- The Lyme Disease Spirochete - Jennifer Miller, Ph.D

Outer-surface protein C of the Lyme disease spirochete: A protein induced in ticks for infection of mammals

THE BURGEONING MOLECULAR GENETICS OF THE LYME DISEASE SPIROCHAETE

Borrelia burgdorferi OspC Protein Required Exclusively in a Crucial Early Stage of Mammalian Infection

Week 7

Helicobacter pylori

Transgenic expression of Helicobacter pylori CagA induces gastrointestinal and hematopoietic neoplasms in mouse

Helicobacter exploits integrin for type IV secretion and kinase activation

"Preparing the shot" Direct injection of proteins into host cells is one of the tricks bacteria use during infection. It seems that, to achieve this, the stomach pathogen Helicobacter pylori first grabs the cell by its surface receptors.